Seroepidemiological study of visceral leishmaniasis and cattle as a possible reservoir host at Trishal Upazila in Bangladesh
نویسندگان
چکیده
To study the effect of months, seasons, age and sex on visceral leishmaniasis (VL) in human, data were collected during March 2010 through February 2011 from the register book of Upazila Health Complex (UHC) of Trishal, which is an endemic region for VL in the Mymensingh district. Besides, 70 blood samples were collected from suspected VL human patients to compare microscopy with rK39 immunochromatographic strip test. Additionally, 50 cattle blood samples were also collected from houses with active or recently-treated VL patients to determine the possible animal reservoir of VL through rK39 strip test. Of the suspected VL patients in the UHC registered book, 43.8% were seropositive. The percentages of seropositive cases were higher in September (73.3%), November (67.2%) and August (65.5%) than in May (18.5%), June (27.5%) and March (36.7%). The rainy season (58.4%) and the winter season (50.6%) showed higher seropositive than the summer (30.7%) season which was significant (p≤ 0.001). Hospital cases of VL were significantly (p≤0.05) higher in 3-14 years (49.3%) and 15-45 years (43.5%) than in children <3 years (32.1%) and adults aged >45 years (33.6%) people. The estimated sensitivity of rK39 strip test and microscopic examination were 100% and 58.8%, respectively and the specificity were 72% and 100%, respectively. Only two cattle blood samples were found positive to rK39 strip test. Our present study indicates that rK39 strip test is superior to the diagnosis of VL compared with parasitological confirmation by direct microscopy of the peripheral blood. Further works are needed to focus on molecular approaches for diagnosis and epidemiological study of VL, sand flies investigation and to confirm the cattle as animal reservoir for VL transmission.
منابع مشابه
Active and passive case detection strategies for the control of leishmaniasis in Bangladesh.
SETTING Two subdistricts in Bangladesh, Fulbaria and Trishal, which are hyperendemic for leishmaniasis. OBJECTIVE To determine 1) the numbers of patients diagnosed with visceral leishmaniasis (VL) and post-kala azar dermal leishmaniasis (PKDL) using an active case detection (ACD) strategy in Fulbaria and a passive case detection (PCD) strategy in Trishal, and 2) the time taken from symptoms t...
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BACKGROUND The visceral leishmaniasis (VL) elimination program in Bangladesh is in its attack phase. The primary goal of this phase is to decrease the burden of VL as much as possible. Active case detection (ACD) by the fever camp method and an approach using past VL cases in the last 6-12 months have been found useful for detection of VL patients in the community. We aimed to explore the yield...
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Background: Leishmaniasis is an infection caused by a protozoan of the genus Leishmania. This descriptive and cross-sectional study was done in order to determine the seroepidemiology of visceral leishmaniasis in East Myankooh area, in Lorestan Province during 2004 – 2005 time period. Materials and methods: This study was a descriptive, cross-sectional study. Multi stage sampling was performed...
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BACKGROUND Visceral leishmaniasis (VL), caused by an intracellular parasite Leishmania donovani in the Indian subcontinent, is considered to be anthroponotic. The role of domestic animals in its transmission is still unclear. Although cattle are the preferred blood host for Phlebotomus argentipes, the sandfly vector of VL in the Indian subcontinent, very little information is available for thei...
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